Nheyo dze photoacoustic imaging

Nheyo dze photoacoustic imaging

Photoacoustic Imaging (PAI) inzira yekurapa yekufungidzira inosanganisaopticsuye acoustics kugadzira ultrasonic masaini uchishandisa kupindirana kwechiedzanematishu kuti uwane yakakwirira-resolution tishu mifananidzo. Inoshandiswa zvakanyanya muminda yebiomedical, kunyanya mukuona bundu, vascular imaging, imaging yeganda uye mamwe minda.

Musimboti:
1. Kutora chiedza uye kuwedzera kwekupisa: - Photoacoustic imaging inoshandisa thermal effect inogadzirwa nechiedza. Mamorekuru e pigment ari munyama (semuenzaniso, hemoglobin, melanin) anotora maphoton (kazhinji ari pedyo ne-infrared light), ayo anoshandurwa kuita simba rekupisa, zvichiita kuti tembiricha yemunzvimbo ikwire.
2. Kuwedzera kupisa kunokonzeresa ultrasound: – Kukwira kwe tembiricha kunotungamira kudiki kuwedzeredza kwetishu, izvo zvinoburitsa masaisai epressure (kureva ultrasound).
3. Ultrasonic kucherechedzwa: – Iwo anogadzirwa ultrasonic masaisai anopararira mukati mematishu, uye aya masaini anozogamuchirwa uye anorekodhwa nea ultrasonic sensors (senge ultrasonic probes).
4. Kugadziriswa kwechifananidzo: iyo yakaunganidzwa ultrasonic chiratidzo inotarirwa uye inogadziriswa kuti ivakezve chimiro uye basa remufananidzo wetishu, iyo inogona kupa optical absorption maitiro emucheka. Zvakanakira zvefotoacoustic imaging: Musiyano wepamusoro: Photoacoustic imaging inovimba nemwenje wekubata maitiro ematishu, uye akasiyana matissue (akadai seropa, mafuta, tsandanyama, zvichingodaro.) ane hunyanzvi hwakasiyana hwekutora chiedza, saka hunogona kupa mifananidzo yakasarudzika. Kugadziriswa kwepamusoro: Uchishandisa iyo yakakwira spatial resolution ye ultrasound, photoacoustic imaging inogona kuwana millimeter kana kunyange sub-millimeter imaging yechokwadi. Isiri-inovhiringidza: Photoacoustic imaging haina-invasive, chiedza uye ruzha hazvizokonzerese kukuvara kwetishu, yakakodzera kwazvo kuongororwa kwekurapa kwevanhu. Kudzika kwekufungidzira kugona: Kuenzaniswa neyechinyakare optical imaging, photoacoustic imaging inogona kupinda akati wandei masendimita pasi peganda, iyo inokodzera yakadzika matishu imaging.

Application:
1. Vascular imaging: - Photoacoustic imaging inogona kuona chiedza-chinopinza chehemoglobin muropa, saka inogona kunyatsoratidza chimiro uye oxygenation mamiriro emidziyo yeropa yekutarisa microcirculation uye kutonga zvirwere.
2. Kuonekwa kwebundu: – Angiogenesis mumatishu ebundu kazhinji kacho kuwanda zvakanyanya, uye photoacoustic imaging inogona kubatsira kukurumidza kuona mabundu nekuona kusagadzikana muvascular structure.
3. Functional imaging: - Photoacoustic imaging inogona kuongorora kupiwa kweokisijeni yematishu nekuona kuwanda kweokisijeni uye deoxyhemoglobin mumatishu, izvo zvakakosha zvikuru pakuongorora kwekushanda kwezvirwere zvakaita sekenza uye chirwere chemoyo.
4. Skin imaging: - Nekuti photoacoustic imaging inotapukira kune epamusoro tishu, yakakodzera kukurumidza kuonekwa kenza yeganda uye kuongororwa kweganda risingaite.
5. Brain imaging: Photoacoustic imaging inogona kuwana cerebral blood flow information nenzira isiri-invasive yekudzidza zvirwere zveuropi zvakadai sesitiroko uye pfari.

Zvinetso uye nzira dzekusimudzira dzephotoacoustic imaging:
Chitubu chechiedzakusarudzwa: Kupenya kwechiedza kweavelengths akasiyana kwakasiyana, nzira yekusarudza iyo yakakodzera wavelength kuenzanisa kugadzirisa uye kudzika kwemukati kunonetsa. Chiratidzo chekugadzirisa: Kutorwa uye kugadzirisa kweiyo ultrasonic masiginecha kunoda kumhanyisa-kumhanya uye kwakaringana algorithms, uye kuvandudza tekinoroji yekuvakazve mifananidzo kwakakosha zvakare. Multimodal imaging: Photoacoustic imaging inogona kusanganiswa nedzimwe nzira dzekufungidzira (zvakadai seMRI, CT, ultrasound imaging) kuti ipe ruzivo rwakakwana rwebiomedical.

Photoacoustic imaging inyowani uye yakawanda-inoshanda biomedical imaging tekinoroji, ine hunhu hwekusiyana kwepamusoro, kukwidziridzwa kwepamusoro uye kusingapindike. Nekuvandudzwa kwetekinoroji, kufungidzira kwefotoacoustic kune yakafara tarisiro yekushandisa mukuongororwa kwekurapa, basic biology research, kuvandudzwa kwezvinodhaka uye mamwe minda.