Chikwata chakabatana chekutsvagisa kubva kuHarvard Medical School (HMS) neMIT General Hospital vanoti vakakwanisa kugadzirisa kuburitswa kweiyo microdisk laser vachishandisa nzira yePEC etching, kugadzira sosi nyowani nanophotonics uye biomedicine "inovimbisa."
(Kubuda kweiyo microdisk laser kunogona kugadziriswa nePEC etching nzira)
Muminda yenanophotonicsuye biomedicine, microdisklasersuye nanodisk lasers ave kuvimbisamagetsiuye probes. Mune akati wandei maapplication akadai se-on-chip photonic kutaurirana, pa-chip bioimaging, biochemical sensing, uye quantum photon ruzivo rwekugadzirisa, ivo vanofanirwa kuwana laser kubuda mukuona wavelength uye yekupedzisira-yakamanikana bhendi. Nekudaro, zvinoramba zvichinetsa kugadzira microdisk uye nanodisk lasers yeiyi chaiyo wavelength pamwero mukuru. Ikozvino nanofabrication maitiro anosuma kusarongeka kwedhayamita yedhisiki, izvo zvinoita kuti zviome kuwana seti yewavelength mulaser mass processing nekugadzirwa.Zvino, boka revatsvagiri kubva kuHarvard Medical School uye Massachusetts General Hospital's Wellman Center yeOptoelectronic Medicineyakagadzira innovative optochemical (PEC) etching tekinoroji inobatsira kunyatso gadzirisa iyo laser wavelength ye microdisk laser ine subnanometer chaiyo. Basa racho rinoburitswa mujenari Advanced Photonics.
Photochemical etching
Sekureva kwemishumo, nzira nyowani yechikwata inogonesa kugadzirwa kwemicro-disk lasers uye nanodisk laser arrays ane chaiyo, akafanotemerwa emission wavelengths. Kiyi yekubudirira uku ndiko kushandiswa kwePEC etching, iyo inopa inoshanda uye ino scalable nzira yekunyatso-tune wavelength ye microdisc laser. Mune mhinduro dziri pamusoro, timu yakabudirira kuwana indium Gallium arsenide phosphating microdisks yakavharwa nesilika pane indium phosphide column chimiro. Ivo vakabva vagadzirisa laser wavelength yeaya mamicrodisks chaizvo kune yakatemerwa kukosha nekuita photochemical etching mune yakasanganiswa mhinduro yesulfuric acid.
Vakaongororawo maitiro uye masimba eiyo chaiyo photochemical (PEC) etchings. Pakupedzisira, vakatamisa wavelength-tuned microdisk array pane polydimethylsiloxane substrate kuti ibudise yakazvimirira, yakasarudzika laser particles ane akasiyana laser wavelengths. Iyo inokonzeresa microdisk inoratidza iyo yekupedzisira-yakafara bandwidth yelaser emission, neiyolaserpambiru isingasviki 0.6 nm uye yakasarudzika particle isingasviki 1.5 nm.
Kuvhura musuwo kune biomedical application
Mhedzisiro iyi inovhura musuwo kune akawanda matsva nanophotonics uye biomedical application. Semuyenzaniso, akamira ega microdisk lasers anogona kushanda se physico-optical barcodes for heterogeneous biological samples, zvichigonesa kunyorwa kwemamwe maseru marudzi uye kunangwa kweakananga mamorekuru mukuongororwa kwemultiplex.Sero mhando-chaiyo labeling iri kuitwa pachishandiswa akajairwa biomarkers, akadai. se organic fluorophores, quantum dots, uye fluorescent beads, ane yakakura emission linewidths. Nokudaro, marudzi mashomanana chete emasero anogona kunyorwa panguva imwe chete. Kusiyana neizvi, iyo yekupedzisira-yakamanikana bhendi mwenje emission ye microdisk laser ichakwanisa kuziva mamwe marudzi emasero panguva imwe chete.
Chikwata chakaedza uye chakabudirira kuratidza zvakanyatsorongeka microdisk laser particles sebiomarkers, ichishandisa iwo kunyora akajairwa mazamu epithelial masero MCF10A. Nekubuda kwavo kwe-ultra-wideband emission, ma lasers aya anogona kushandura biosensing, achishandisa akapupurirwa biomedical uye optical matekiniki akadai se cytodynamic imaging, kuyerera cytometry, uye akawanda-omics ongororo. Iyo tekinoroji yakavakirwa paPEC etching inoratidza kufambira mberi kukuru mune microdisk lasers. Iyo scalability yenzira, pamwe neiyo subnanometer chaiyo, inovhura mikana mitsva yeasingaverengeke mashandisirwo e lasers mu nanophotonics uye biomedical zvishandiso, pamwe nemabhakodhi emamwe maseru ehuwandu uye analytical mamorekuru.
Nguva yekutumira: Jan-29-2024